3nw9

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===Rat COMT in complex with a methylpurin-containing bisubstrate inhibitor===
===Rat COMT in complex with a methylpurin-containing bisubstrate inhibitor===
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The line below this paragraph, {{ABSTRACT_PUBMED_21538606}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 21538606 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21538606}}
==About this Structure==
==About this Structure==
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[[Category: Catechol O-methyltransferase]]
[[Category: Catechol O-methyltransferase]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Benz, J.]]
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[[Category: Ehler, A.]]
[[Category: Rudolph, M G.]]
[[Category: Rudolph, M G.]]
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[[Category: Schlatter, D.]]
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[[Category: Stihle, M.]]
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[[Category: Alternative initiation]]
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[[Category: Catecholamine metabolism]]
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[[Category: Cell membrane]]
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[[Category: Magnesium]]
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[[Category: Membrane]]
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[[Category: Metal-binding]]
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[[Category: Methyltransferase]]
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[[Category: Neurotransmitter degradation]]
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[[Category: S-adenosyl-l-methionine]]
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[[Category: Signal-anchor]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 05:21, 23 May 2012

Template:STRUCTURE 3nw9

Rat COMT in complex with a methylpurin-containing bisubstrate inhibitor

Template:ABSTRACT PUBMED 21538606

About this Structure

3nw9 is a 1 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Ellermann M, Paulini R, Jakob-Roetne R, Lerner C, Borroni E, Roth D, Ehler A, Schweizer WB, Schlatter D, Rudolph MG, Diederich F. Molecular Recognition at the Active Site of Catechol-O-methyltransferase (COMT): Adenine Replacements in Bisubstrate Inhibitors. Chemistry. 2011 May 27;17(23):6369-81. doi: 10.1002/chem.201003648. Epub, 2011 Apr 27. PMID:21538606 doi:10.1002/chem.201003648

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OCA

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