4epv

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'''Unreleased structure'''
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[[Image:4epv.jpg|left|200px]]
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The entry 4epv is ON HOLD until Paper Publication
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{{STRUCTURE_4epv| PDB=4epv | SCENE= }}
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Authors: Sun, Q., Burke, J.P., Phan, J., Burns, M.C., Olejniczak, E.T., Waterson, A.G., Lee, T., Rossanese, O.W., Fesik, S.W.
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===Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-mediated Activation===
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Description: Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-mediated Activation
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{{ABSTRACT_PUBMED_22566140}}
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==About this Structure==
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[[4epv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EPV OCA].
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==Reference==
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<ref group="xtra">PMID:022566140</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Small monomeric GTPase]]
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[[Category: Burke, J P.]]
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[[Category: Burns, M C.]]
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[[Category: Fesik, S W.]]
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[[Category: Lee, T.]]
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[[Category: Olejniczak, E T.]]
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[[Category: Phan, J.]]
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[[Category: Rossanese, O W.]]
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[[Category: Sun, Q.]]
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[[Category: Waterson, A G.]]
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[[Category: Binder]]
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[[Category: Cytosol]]
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[[Category: Hydrolase]]
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[[Category: Inhibitor of sos-mediated activation]]
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[[Category: Pi3k]]
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[[Category: Raf]]
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[[Category: Ral]]
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[[Category: Signaling transduction]]
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[[Category: Small gtpase]]
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[[Category: So]]

Revision as of 06:06, 23 May 2012

Image:4epv.jpg

Template:STRUCTURE 4epv

Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-mediated Activation

Template:ABSTRACT PUBMED 22566140

About this Structure

4epv is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Sun Q, Burke JP, Phan J, Burns MC, Olejniczak ET, Waterson AG, Lee T, Rossanese OW, Fesik SW. Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation. Angew Chem Int Ed Engl. 2012 May 8. doi: 10.1002/anie.201201358. PMID:22566140 doi:10.1002/anie.201201358

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OCA

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