1gt7
From Proteopedia
(New page: 200px<br /> <applet load="1gt7" size="450" color="white" frame="true" align="right" spinBox="true" caption="1gt7, resolution 2.7Å" /> '''L-RHAMNULOSE-1-PHOSP...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1GT7 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]] with ZN and PGH as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.19 4.1.2.19]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GT7 OCA]]. | + | 1GT7 is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]] with ZN and PGH as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Rhamnulose-1-phosphate_aldolase Rhamnulose-1-phosphate aldolase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.19 4.1.2.19]]. Structure known Active Site: ZNA. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GT7 OCA]]. |
==Reference== | ==Reference== | ||
The structure of L-rhamnulose-1-phosphate aldolase (class II) solved by low-resolution SIR phasing and 20-fold NCS averaging., Kroemer M, Schulz GE, Acta Crystallogr D Biol Crystallogr. 2002 May;58(Pt 5):824-32. Epub 2002, Apr 26. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11976494 11976494] | The structure of L-rhamnulose-1-phosphate aldolase (class II) solved by low-resolution SIR phasing and 20-fold NCS averaging., Kroemer M, Schulz GE, Acta Crystallogr D Biol Crystallogr. 2002 May;58(Pt 5):824-32. Epub 2002, Apr 26. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11976494 11976494] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| + | [[Category: Rhamnulose-1-phosphate aldolase]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Kroemer, M.]] | [[Category: Kroemer, M.]] | ||
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[[Category: zinc enzyme]] | [[Category: zinc enzyme]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:18:38 2007'' |
Revision as of 11:13, 30 October 2007
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L-RHAMNULOSE-1-PHOSPHATE ALDOLASE FROM ESCHERICHIA COLI
Overview
The enzyme L-rhamnulose-1-phosphate aldolase catalyzes the reversible, cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate and, L-lactaldehyde. It is a homotetramer with an M(r) of 30 000 per subunit, and crystallized in space group P3(2)21. The enzyme shows a low sequence, identity of 18% with the structurally known L-fuculose-1-phosphate, aldolase that splits a stereoisomer in a similar reaction. Structure, analysis was initiated with a single heavy-atom derivative measured to 6 A, resolution. The resulting poor electron density, a self-rotation function, and the working hypothesis that both enzymes are C(4) symmetric with, envelopes that resemble one another allowed the location of the 20, protomers of the asymmetric unit. The crystal-packing unit was a, D(4)-symmetric ... [(full description)]
About this Structure
1GT7 is a [Single protein] structure of sequence from [Escherichia coli] with ZN and PGH as [ligands]. Active as [Rhamnulose-1-phosphate aldolase], with EC number [4.1.2.19]. Structure known Active Site: ZNA. Full crystallographic information is available from [OCA].
Reference
The structure of L-rhamnulose-1-phosphate aldolase (class II) solved by low-resolution SIR phasing and 20-fold NCS averaging., Kroemer M, Schulz GE, Acta Crystallogr D Biol Crystallogr. 2002 May;58(Pt 5):824-32. Epub 2002, Apr 26. PMID:11976494
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