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1fre
From Proteopedia
(New page: 200px<br /> <applet load="1fre" size="450" color="white" frame="true" align="right" spinBox="true" caption="1fre" /> '''XNF7 BBOX, DEVELOPMENTAL PROTEIN, PH 7.5, 3...) |
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==About this Structure== | ==About this Structure== | ||
| - | 1FRE is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]] with ZN as [[http://en.wikipedia.org/wiki/ligand ligand]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1FRE OCA]]. | + | 1FRE is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]] with ZN as [[http://en.wikipedia.org/wiki/ligand ligand]]. Structure known Active Site: ZN1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1FRE OCA]]. |
==Reference== | ==Reference== | ||
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[[Category: zinc-binding protein]] | [[Category: zinc-binding protein]] | ||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:18:45 2007'' |
Revision as of 11:14, 30 October 2007
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XNF7 BBOX, DEVELOPMENTAL PROTEIN, PH 7.5, 30 C, WITH ZINC, NMR, 1 STRUCTURE
Overview
Xenopus nuclear factor XNF7, a maternally expressed protein, functions in, patterning of the embryo. XNF7 contains a number of defined protein, domains implicated in the regulation of some developmental processes., Among these is a tripartite motif comprising a zinc-binding RING finger, and B-box domain next to a predicted alpha-helical coiled-coil domain., Interestingly, this motif is found in a variety of protein including, several proto-oncoproteins. Here we describe the solution structure of the, XNF7 B-box zinc-binding domain determined at physiological pH by 1H NMR, methods. The B-box structure represents the first three-dimensional, structure of this new motif and comprises a monomer have two beta-strands, two helical turns and three extended loop regions packed in a novel, ... [(full description)]
About this Structure
1FRE is a [Single protein] structure of sequence from [Xenopus laevis] with ZN as [ligand]. Structure known Active Site: ZN1. Full crystallographic information is available from [OCA].
Reference
Novel topology of a zinc-binding domain from a protein involved in regulating early Xenopus development., Borden KL, Lally JM, Martin SR, O'Reilly NJ, Etkin LD, Freemont PS, EMBO J. 1995 Dec 1;14(23):5947-56. PMID:8846787
Page seeded by OCA on Tue Oct 30 13:18:45 2007
