4epr
From Proteopedia
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{{STRUCTURE_4epr| PDB=4epr | SCENE= }} | {{STRUCTURE_4epr| PDB=4epr | SCENE= }} | ||
| - | === | + | ===Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation.=== |
Revision as of 04:50, 30 May 2012
Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation.
Template:ABSTRACT PUBMED 22566140
About this Structure
4epr is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Sun Q, Burke JP, Phan J, Burns MC, Olejniczak ET, Waterson AG, Lee T, Rossanese OW, Fesik SW. Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation. Angew Chem Int Ed Engl. 2012 May 8. doi: 10.1002/anie.201201358. PMID:22566140 doi:10.1002/anie.201201358
Categories: Homo sapiens | Small monomeric GTPase | Burke, J P. | Burns, M C. | Fesik, S W. | Lee, T. | Olejniczak, E T. | Phan, J. | Rossanese, O W. | Sun, Q | Waterson, A G. | Binder | Closed conformation | Gtp-binding protein | Hydrolase | Inhibitor of sos-mediated activation | Kra | Oncogene | P21
