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2h51

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Image:2h51.png

Template:STRUCTURE 2h51

Contents

Crystal structure of human caspase-1 (Glu390->Asp and Arg286->Lys) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)

Template:ABSTRACT PUBMED 18590738

About this Structure

2h51 is a 3 chain structure of Caspase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Datta D, Scheer JM, Romanowski MJ, Wells JA. An allosteric circuit in caspase-1. J Mol Biol. 2008 Sep 19;381(5):1157-67. Epub 2008 Jun 20. PMID:18590738 doi:10.1016/j.jmb.2008.06.040
  • Fang B, Boross PI, Tozser J, Weber IT. Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition. J Mol Biol. 2006 Jul 14;360(3):654-66. Epub 2006 Jun 2. PMID:16781734 doi:10.1016/j.jmb.2006.05.041

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OCA

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