2c7v

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Revision as of 08:51, 2 June 2012

Image:2c7v.png

Template:STRUCTURE 2c7v

STRUCTURE OF TRYPANOSOMA BRUCEI PTERIDINE REDUCTASE (PTR1) IN TERNARY COMPLEX WITH COFACTOR AND THE ANTIFOLATE METHOTREXATE

Template:ABSTRACT PUBMED 16968221

About this Structure

2c7v is a 4 chain structure with sequence from Trypanosoma brucei brucei. Full crystallographic information is available from OCA.

Reference

  • Dawson A, Gibellini F, Sienkiewicz N, Tulloch LB, Fyfe PK, McLuskey K, Fairlamb AH, Hunter WN. Structure and reactivity of Trypanosoma brucei pteridine reductase: inhibition by the archetypal antifolate methotrexate. Mol Microbiol. 2006 Sep;61(6):1457-68. PMID:16968221 doi:10.1111/j.1365-2958.2006.05332.x

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