3k1o
From Proteopedia
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Revision as of 09:33, 2 June 2012
Crystal structure of sterol 14-alpha demethylase (CYP51) from Trypanosoma cruzi in complex with a potential antichagasic drug, posaconazole
Template:ABSTRACT PUBMED 20530488
About this Structure
3k1o is a 1 chain structure with sequence from Trypanosoma cruzi. Full crystallographic information is available from OCA.
Reference
- Lepesheva GI, Hargrove TY, Anderson S, Kleshchenko Y, Furtak V, Wawrzak Z, Villalta F, Waterman MR. Structural insights into inhibition of sterol 14alpha-demethylase in the human pathogen Trypanosoma cruzi. J Biol Chem. 2010 Aug 13;285(33):25582-90. Epub 2010 Jun 8. PMID:20530488 doi:10.1074/jbc.M110.133215
Categories: Sterol 14-demethylase | Trypanosoma cruzi | Anderson, S. | Hargrove, T Y. | Lepesheva, G I | Waterman, M R. | Wawrzak, Z. | Cyp51 | Cytochrome p450 | Eburicol 14a-demethylase | Endoplasmic reticulum | Heme | Heme-thiolate protein | Iron | Lipid | Membrane | Monooxygenase | Oxidoreductase | Sterol 14-alpha demethylase | Sterol biosynthesis | Transmembrane protein
