2oz2
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Revision as of 09:55, 2 June 2012
Crystal structure analysis of cruzain bound to vinyl sulfone derived inhibitor (K11777)
Template:ABSTRACT PUBMED 19620707
About this Structure
2oz2 is a 2 chain structure with sequence from Trypanosoma cruzi. Full crystallographic information is available from OCA.
Reference
- Kerr ID, Lee JH, Farady CJ, Marion R, Rickert M, Sajid M, Pandey KC, Caffrey CR, Legac J, Hansell E, McKerrow JH, Craik CS, Rosenthal PJ, Brinen LS. Vinyl sulfones as antiparasitic agents and a structural basis for drug design. J Biol Chem. 2009 Sep 18;284(38):25697-703. Epub 2009 Jul 20. PMID:19620707 doi:10.1074/jbc.M109.014340
