1k74
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Revision as of 15:25, 2 June 2012
Contents |
The 2.3 Angstrom resolution crystal structure of the heterodimer of the human PPARgamma and RXRalpha ligand binding domains respectively bound with GW409544 and 9-cis retinoic acid and co-activator peptides.
Template:ABSTRACT PUBMED 11698662
About this Structure
1k74 is a 4 chain structure of Peroxisome Proliferator-Activated Receptors with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Xu HE, Lambert MH, Montana VG, Plunket KD, Moore LB, Collins JL, Oplinger JA, Kliewer SA, Gampe RT Jr, McKee DD, Moore JT, Willson TM. Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13919-24. Epub 2001 Nov 6. PMID:11698662 doi:10.1073/pnas.241410198
Categories: Homo sapiens | Collins, J L. | Gampe, R T. | Kliewer, S A. | Lambert, M H. | McKee, D D. | Montana, V G. | Moore, J T. | Moore, L B. | Oplinger, J A. | Willson, T M. | Xu, H E. | The heterodimer of the nuclear receptor ligand binding domains of rxralpha and ppargamma bound respectively with 9-cis retinoic acid and gw409544 and coactivator peptide | Transcription
