3b8r

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Revision as of 15:29, 2 June 2012

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Template:STRUCTURE 3b8r

Contents 1 Crystal structure of the VEGFR2 kinase domain in complex with a naphthamide inhibitor 2 About this Structure 3 See Also 4 Reference

Crystal structure of the VEGFR2 kinase domain in complex with a naphthamide inhibitor

Template:ABSTRACT PUBMED 18324759

About this Structure

3b8r is a 2 chain structure of Vascular Endothelial Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Vascular Endothelial Growth Factor Receptor

Reference

• Weiss MM, Harmange JC, Polverino AJ, Bauer D, Berry L, Berry V, Borg G, Bready J, Chen D, Choquette D, Coxon A, Demelfi T, Doerr N, Estrada J, Flynn J, Graceffa RF, Harriman SP, Kaufman S, La DS, Long A, Neervannan S, Patel VF, Potashman M, Regal K, Roveto PM, Schrag ML, Starnes C, Tasker A, Teffera Y, Whittington DA, Zanon R. Evaluation of a series of naphthamides as potent, orally active vascular endothelial growth factor receptor-2 tyrosine kinase inhibitors. J Med Chem. 2008 Mar 27;51(6):1668-80. Epub 2008 Mar 7. PMID:18324759 doi:10.1021/jm701098w