3cpc

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Revision as of 15:45, 2 June 2012

Image:3cpc.png

Template:STRUCTURE 3cpc

Contents

Crystal structure of the VEGFR2 kinase domain in complex with a pyridone inhibitor

Template:ABSTRACT PUBMED 18447379

About this Structure

3cpc is a 2 chain structure of Vascular Endothelial Growth Factor Receptor with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Hu E, Tasker A, White RD, Kunz RK, Human J, Chen N, Burli R, Hungate R, Novak P, Itano A, Zhang X, Yu V, Nguyen Y, Tudor Y, Plant M, Flynn S, Xu Y, Meagher KL, Whittington DA, Ng GY. Discovery of Aryl Aminoquinazoline Pyridones as Potent, Selective, and Orally Efficacious Inhibitors of Receptor Tyrosine Kinase c-Kit. J Med Chem. 2008 Jun 12;51(11):3065-8. Epub 2008 May 1. PMID:18447379 doi:http://dx.doi.org/10.1021/jm800188g

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