Nucleosomes

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<scene name='1aoi/Introduction/2'>The nucleosome core particle</scene> contains two copies of each histone <font color=tan>'''protein'''</font> (<font color=tan>'''H2A, H2B, H3, H4'''</font>) and 146 basepairs (bp) of superhelical <font color=purple>'''DNA'''</font> wrapped around this histone octamer. It represents the first order of DNA packaging in the nucleus and as such is the principal structure that determines DNA accessibility (created by David Marcey, Eran Hodis, Jaime Prilusky).<br />
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<scene name='1aoi/Introduction/2'>The nucleosome core particle</scene> contains two copies of each histone <font color=tan>'''protein'''</font> (<font color=tan>'''H2A, H2B, H3, H4'''</font>) and 146 basepairs (bp) of superhelical <font color=purple>'''DNA'''</font> wrapped around this histone octamer. It represents the first order of DNA packaging in the nucleus and as such is the principal structure that determines DNA accessibility (this scene was created by David Marcey, Eran Hodis, Jaime Prilusky).<br />
Examples of [[Archaeal_Histones]]
Examples of [[Archaeal_Histones]]
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Revision as of 10:28, 3 June 2012

For a general introduction beyond what is provided below, please see Wikipedia: Nucleosome. For a list of nucleosome structures, see Category: Nucleosome.

Scenes for Projection in Biochemistry Classes

This section offers some large scenes of a nucleosome (1aoi), as determined in Tim Richmond's lab, suitable for projection in biochemistry classes.

1aoi, resolution 2.80Å

Drag the structure with the mouse to rotate

1. : DNA, Protein.

2.

3.
   H2a   H2b   H3   H4


4.

contains two copies of each histone protein (H2A, H2B, H3, H4) and 146 basepairs (bp) of superhelical DNA wrapped around this histone octamer. It represents the first order of DNA packaging in the nucleus and as such is the principal structure that determines DNA accessibility (this scene was created by David Marcey, Eran Hodis, Jaime Prilusky).
Examples of Archaeal_Histones

3D structures of histone

Histone

Additional Resources

For Additional Information, See: Nucleic Acids

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