4ajw
From Proteopedia
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Revision as of 06:51, 6 June 2012
Discovery and Optimization of New Benzimidazole- and Benzoxazole-Pyrimidone Selective PI3KBeta Inhibitors for the Treatment of Phosphatase and TENsin homologue (PTEN)-Deficient Cancers"
Template:ABSTRACT PUBMED 22524426
About this Structure
4ajw is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Certal V, Halley F, Virone-Oddos A, Delorme C, Karlsson A, Rak A, Thompson F, Filoche-Romme B, El-Ahmad Y, Carry JC, Abecassis PY, Lejeune P, Vincent L, Bonnevaux H, Nicolas JP, Bertrand T, Marquette JP, Michot N, Benard T, Below P, Vade I, Chatreaux F, Lebourg G, Pilorge F, Angouillant-Boniface O, Louboutin A, Lengauer C, Schio L. Discovery and Optimization of New Benzimidazole- and Benzoxazole-Pyrimidone Selective PI3Kbeta Inhibitors for the Treatment of Phosphatase and TENsin homologue (PTEN)-Deficient Cancers. J Med Chem. 2012 May 2. PMID:22524426 doi:10.1021/jm300241b
Categories: Mus musculus | Phosphatidylinositol-4,5-bisphosphate 3-kinase | Abecassis, P Y. | Angouillant-Boniface, O. | Below, P. | Benard, T. | Bertrand, T. | Bonnevaux, H. | Carry, J C. | Certal, V. | Chatreaux, F. | Delorme, C. | El-Ahmad, Y. | Filoche-Romme, B. | Halley, F. | Karlsson, A. | Lebourg, G. | Lejeune, P. | Lengauer, C. | Louboutin, A. | Marquette, J P. | Michot, N. | Nicolas, J P. | Pilorge, F. | Rak, A. | Schio, L. | Thompson, F. | Vade, I. | Virone-Oddos, A. | P110d | Transferase
