4ehr

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'''Unreleased structure'''
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[[Image:4ehr.jpg|left|200px]]
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The entry 4ehr is ON HOLD until Paper Publication
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{{STRUCTURE_4ehr| PDB=4ehr | SCENE= }}
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Authors: Schroeder, G.M., Wei, D., Banfi, P., Cai, Z., Lippy, J., Menichincheri, M., Modugno, M., Naglich, J., Penhallow, B., Perez, H.L., Sack, J., Schmidt, R.J., Tebben, A., Yan, C., Zhang, L., Galvani, A., Lombardo, L.J., Borzilleri, R.M.
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===Crystal structure of Bcl-Xl complex with 4-(5-butyl-3-(hydroxymethyl)-1-phenyl-1h-pyrazol-4-yl)-3-(3,4-dihydro-2(1h)-isoquinolinylcarbonyl)-n-((2-(trimethylsilyl)ethyl)sulfonyl)benzamide===
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Description: Crystal structure of Bcl-Xl complex with 4-(5-butyl-3-(hydroxymethyl)-1-phenyl-1h-pyrazol-4-yl)-3-(3,4-dihydro-2(1h)-isoquinolinylcarbonyl)-n-((2-(trimethylsilyl)ethyl)sulfonyl)benzamide
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{{ABSTRACT_PUBMED_22608393}}
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==About this Structure==
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[[4ehr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EHR OCA].
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==Reference==
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<ref group="xtra">PMID:022608393</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
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[[Category: Banfi, P.]]
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[[Category: Borzilleri, R M.]]
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[[Category: Cai, Z.]]
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[[Category: Galvani, A.]]
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[[Category: Lippy, J.]]
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[[Category: Lombardo, L J.]]
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[[Category: Menichincheri, M.]]
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[[Category: Modugno, M.]]
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[[Category: Naglich, J.]]
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[[Category: Penhallow, B.]]
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[[Category: Perez, H L.]]
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[[Category: Sack, J.]]
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[[Category: Schmidt, R J.]]
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[[Category: Schroeder, G M.]]
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[[Category: Tebben, A.]]
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[[Category: Wei, D.]]
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[[Category: Yan, C.]]
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[[Category: Zhang, L.]]
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[[Category: Apoptosis]]
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[[Category: Bcl-2 family]]
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[[Category: Programmed cell death]]

Revision as of 07:44, 6 June 2012

Image:4ehr.jpg

Template:STRUCTURE 4ehr

Crystal structure of Bcl-Xl complex with 4-(5-butyl-3-(hydroxymethyl)-1-phenyl-1h-pyrazol-4-yl)-3-(3,4-dihydro-2(1h)-isoquinolinylcarbonyl)-n-((2-(trimethylsilyl)ethyl)sulfonyl)benzamide

Template:ABSTRACT PUBMED 22608393

About this Structure

4ehr is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Schroeder GM, Wei D, Banfi P, Cai ZW, Lippy J, Menichincheri M, Modugno M, Naglich J, Penhallow B, Perez HL, Sack J, Schmidt RJ, Tebben A, Yan C, Zhang L, Galvani A, Lombardo LJ, Borzilleri RM. Pyrazole and pyrimidine phenylacylsulfonamides as dual Bcl-2/Bcl-xL antagonists. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3951-6. Epub 2012 Apr 30. PMID:22608393 doi:10.1016/j.bmcl.2012.04.106

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OCA

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