2fb4
From Proteopedia
(New page: 200px<br /> <applet load="2fb4" size="450" color="white" frame="true" align="right" spinBox="true" caption="2fb4, resolution 1.9Å" /> '''DIR PRIMAERSTRUKTUR ...) |
|||
| Line 1: | Line 1: | ||
| - | [[Image:2fb4. | + | [[Image:2fb4.jpg|left|200px]]<br /><applet load="2fb4" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="2fb4" size=" | + | |
caption="2fb4, resolution 1.9Å" /> | caption="2fb4, resolution 1.9Å" /> | ||
'''DIR PRIMAERSTRUKTUR DES KRISTALLISIERBAREN MONOKLONALEN IMMUNOGLOBULINS IGG1 KOL. II. AMINOSAEURESEQUENZ DER L-KETTE, LAMBDA-TYP, SUBGRUPPE I (GERMAN)'''<br /> | '''DIR PRIMAERSTRUKTUR DES KRISTALLISIERBAREN MONOKLONALEN IMMUNOGLOBULINS IGG1 KOL. II. AMINOSAEURESEQUENZ DER L-KETTE, LAMBDA-TYP, SUBGRUPPE I (GERMAN)'''<br /> | ||
| Line 8: | Line 7: | ||
==About this Structure== | ==About this Structure== | ||
| - | 2FB4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure superseeds the now removed PDB entry 1FB4. Full crystallographic information is available from [http:// | + | 2FB4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure superseeds the now removed PDB entry 1FB4. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FB4 OCA]. |
==Reference== | ==Reference== | ||
| Line 18: | Line 17: | ||
[[Category: immunoglobulin]] | [[Category: immunoglobulin]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Feb 15 17:24:54 2008'' |
Revision as of 15:24, 15 February 2008
|
DIR PRIMAERSTRUKTUR DES KRISTALLISIERBAREN MONOKLONALEN IMMUNOGLOBULINS IGG1 KOL. II. AMINOSAEURESEQUENZ DER L-KETTE, LAMBDA-TYP, SUBGRUPPE I (GERMAN)
Overview
The immunoglobulin Kol was the first intact antibody molecule which was, characterized by high-resolution X-ray crystallography. Furthermore the, complete amino-acid sequence of the heavy (H)-chain is known. Here we, report the complete amino-acid sequence of the light (L)-chain of the, monoclonal immunoglobulin Kol (IgG1). The polypeptide has an Mr of 22,781, consists of 216 amino acids and due to its structure is of the, lambda-type. With the characteristic amino acids threonine, asparagine, threonine, glycine and lysine in positions 101, 114, 116, 154, and 165, respectively the Kol L-chain is of the Mcg isotype. With the proteins Mcg, Mot, Bur, Loc and Mem six myeloma-derived amino-acid sequences of the same, isotype are known. The amino-acid sequence of the N-terminal variable part, is characteristic of subgroup 1. This contribution completes the primary, structure of IgG1 Kol.
About this Structure
2FB4 is a Single protein structure of sequence from Homo sapiens. This structure superseeds the now removed PDB entry 1FB4. Full crystallographic information is available from OCA.
Reference
[The primary structure of crystallizable monoclonal immunoglobulin IgG1 Kol. II. Amino acid sequence of the L-chain, gamma-type, subgroup I], Kratzin HD, Palm W, Stangel M, Schmidt WE, Friedrich J, Hilschmann N, Biol Chem Hoppe Seyler. 1989 Mar;370(3):263-72. PMID:2713105
Page seeded by OCA on Fri Feb 15 17:24:54 2008
