Histone methyltransferase
From Proteopedia
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== 3D Structures of histone methyltransferase == | == 3D Structures of histone methyltransferase == | ||
| - | ''Updated | + | ''Updated June 2012'' |
[[1nw3]] – hHMT DOT1L – human | [[1nw3]] – hHMT DOT1L – human | ||
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[[3s8s]] – hKHMT SETD1A RRM domain<br /> | [[3s8s]] – hKHMT SETD1A RRM domain<br /> | ||
| + | [[2r3a]] – hKHMT Suv39H2<br /> | ||
| + | [[3rq4]] - hKHMT Suv420H2<br /> | ||
| + | [[3s8p]] - hKHMT Suv420H1<br /> | ||
| + | [[3mts]] - hKHMT Suv39H1 chromo domain<br /> | ||
[[1h3i]] - hKHMT SET7/9 residues 52-344<br /> | [[1h3i]] - hKHMT SET7/9 residues 52-344<br /> | ||
[[1o9s]] - hKHMT SET7/9 residues 52-344 + H3 peptide<br /> | [[1o9s]] - hKHMT SET7/9 residues 52-344 + H3 peptide<br /> | ||
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[[3s7d]], [[3s7f]], [[3tg5]] - hKHMT Smyd2 + SAH + p53 peptide | [[3s7d]], [[3s7f]], [[3tg5]] - hKHMT Smyd2 + SAH + p53 peptide | ||
| - | [[3s7j]], [[3tg4]] - hKHMT Smyd2 + SAM | + | [[3s7j]], [[3tg4]] - hKHMT Smyd2 + SAM<br /> |
| + | [[1ml9]] – NcKHMT Dim-5 – ''Neurospora crassa''<br /> | ||
| + | [[1peg]] - NcKHMT Dim-5 + H3 peptide<br /> | ||
| + | [[1n3j]] – PvKHMT – Paramecium bursaria chlorella virus<br /> | ||
| + | [[2g46]] – PvKHMT + SAH + H3 peptide<br /> | ||
| + | [[1u2z ]]– yKHMT C terminal | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 11:33, 13 June 2012
Histone methyltransferase (HMT) are histone-lysine N-methyltransferase (KHMT) and histone-arginine N-methyltransferase (RHMT) which catalyzes the transfer of methyl groups to lysine and arginine residues of histones. HMT use S-adenosyl methionine (SAM) or S-adenosyl homocysteine (SAH) as the methyl donor.
3D Structures of histone methyltransferase
Updated June 2012
1nw3 – hHMT DOT1L – human
2igq – hHMT-1 C terminal
Histone-lysine N-methyltransferase
2j8a – KHMT SET1 RRM domain – yeast
3s8s – hKHMT SETD1A RRM domain
2r3a – hKHMT Suv39H2
3rq4 - hKHMT Suv420H2
3s8p - hKHMT Suv420H1
3mts - hKHMT Suv39H1 chromo domain
1h3i - hKHMT SET7/9 residues 52-344
1o9s - hKHMT SET7/9 residues 52-344 + H3 peptide
2bqz - hKHMT SET7 residues 192-352 + H4 peptide
2o8j - hKHMT H3K9 residues 913-1193
2rfi, 3hna - hKHMT H3K9 catalytic domain + H3 peptide
3n71 - hKHMT Smyd1
3rib – hKHMT Smyd2 + SAH
3s7b - hKHMT Smyd2 + SAM + inhibitor
3s7d, 3s7f, 3tg5 - hKHMT Smyd2 + SAH + p53 peptide
3s7j, 3tg4 - hKHMT Smyd2 + SAM
1ml9 – NcKHMT Dim-5 – Neurospora crassa
1peg - NcKHMT Dim-5 + H3 peptide
1n3j – PvKHMT – Paramecium bursaria chlorella virus
2g46 – PvKHMT + SAH + H3 peptide
1u2z – yKHMT C terminal
