2w26

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{{Seed}}
 
[[Image:2w26.png|left|200px]]
[[Image:2w26.png|left|200px]]
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{{STRUCTURE_2w26| PDB=2w26 | SCENE= }}
{{STRUCTURE_2w26| PDB=2w26 | SCENE= }}
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===FACTOR XA IN COMPLEX WITH BAY59-7939===
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===Fator Xa in complex with BAY59-7939===
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==About this Structure==
==About this Structure==
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2W26 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W26 OCA].
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[[2w26]] is a 2 chain structure of [[Factor Xa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W26 OCA].
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==See Also==
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*[[Factor Xa|Factor Xa]]
==Reference==
==Reference==
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<ref group="xtra">PMID:16161994</ref><references group="xtra"/>
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<ref group="xtra">PMID:016161994</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Lampe, T.]]
[[Category: Lampe, T.]]
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[[Category: Straub, A.]]
[[Category: Straub, A.]]
[[Category: Blood coagulation]]
[[Category: Blood coagulation]]
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[[Category: Calcium]]
 
[[Category: Cleavage on pair of basic residue]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Egf-like domain]]
[[Category: Egf-like domain]]
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[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Hydroxylation]]
[[Category: Hydroxylation]]
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[[Category: Polymorphism]]
 
[[Category: Protease]]
[[Category: Protease]]
[[Category: Secreted]]
[[Category: Secreted]]
[[Category: Serine protease]]
[[Category: Serine protease]]
[[Category: Zymogen]]
[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:41:33 2009''
 

Revision as of 06:50, 20 June 2012

Template:STRUCTURE 2w26

Contents

Fator Xa in complex with BAY59-7939

Template:ABSTRACT PUBMED 16161994

About this Structure

2w26 is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Roehrig S, Straub A, Pohlmann J, Lampe T, Pernerstorfer J, Schlemmer KH, Reinemer P, Perzborn E. Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor. J Med Chem. 2005 Sep 22;48(19):5900-8. PMID:16161994 doi:10.1021/jm050101d

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