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4deg

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Revision as of 06:59, 20 June 2012

Image:4deg.png

Template:STRUCTURE 4deg

Crystal structure of c-Met in complex with triazolopyridazine inhibitor 2

Template:ABSTRACT PUBMED 22595176

About this Structure

4deg is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bode CM, Boezio AA, Albrecht BK, Bellon SF, Berry L, Broome MA, Choquette D, Dussault I, Lewis RT, Lin MH, Rex K, Whittington DA, Yang Y, Harmange JC. Discovery and optimization of a potent and selective triazolopyridinone series of c-Met inhibitors. Bioorg Med Chem Lett. 2012 Jun 15;22(12):4089-93. Epub 2012 Apr 25. PMID:22595176 doi:10.1016/j.bmcl.2012.04.072

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OCA

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