3t5z

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-	'''Unreleased structure'''	+	[[Image:3t5z.jpg|left|200px]]
-	The entry 3t5z is ON HOLD until Paper Publication	+	{{STRUCTURE_3t5z| PDB=3t5z | SCENE= }}
-	Authors: Di Fiore, A., Maresca, A., Alterio, V., Supuran, C.T., De Simone, G.	+	===Crystal structure of the human carbonic anhydrase II in complex with N-methoxy-benzenesulfonamide===
-	Description: Crystal structure of the human carbonic anhydrase II in complex with N-methoxy-benzenesulfonamide	+	{{ABSTRACT_PUBMED_21952494}}
		+
		+	==About this Structure==
		+	[[3t5z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T5Z OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021952494</ref><ref group="xtra">PMID:003151019</ref><ref group="xtra">PMID:019882701</ref><references group="xtra"/>
		+	[[Category: Carbonate dehydratase]]
		+	[[Category: Homo sapiens]]
		+	[[Category: Alterio, V.]]
		+	[[Category: Fiore, A Di.]]
		+	[[Category: Maresca, A.]]
		+	[[Category: Simone, G De.]]
		+	[[Category: Supuran, C T.]]
		+	[[Category: Lyase-lyase inhibitor complex]]
		+	[[Category: Protein-inhibitor complex]]

---

Revision as of 07:45, 20 June 2012

Template:STRUCTURE 3t5z

Crystal structure of the human carbonic anhydrase II in complex with N-methoxy-benzenesulfonamide

Template:ABSTRACT PUBMED 21952494

About this Structure

3t5z is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Di Fiore A, Maresca A, Alterio V, Supuran CT, De Simone G. Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of N-substituted benzenesulfonamides to human isoform II. Chem Commun (Camb). 2011 Nov 14;47(42):11636-8. Epub 2011 Sep 26. PMID:21952494 doi:10.1039/c1cc14575d
• Eriksson AE, Jones TA, Liljas A. Refined structure of human carbonic anhydrase II at 2.0 A resolution. Proteins. 1988;4(4):274-82. PMID:3151019 doi:http://dx.doi.org/10.1002/prot.340040406
• Scott AD, Phillips C, Alex A, Flocco M, Bent A, Randall A, O'Brien R, Damian L, Jones LH. Thermodynamic optimisation in drug discovery: a case study using carbonic anhydrase inhibitors. ChemMedChem. 2009 Dec;4(12):1985-9. PMID:19882701 doi:10.1002/cmdc.200900386