3ncg
From Proteopedia
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===Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with bumped kinase inhibitor NM-PP1=== | ===Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with bumped kinase inhibitor NM-PP1=== | ||
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Revision as of 08:04, 20 June 2012
Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with bumped kinase inhibitor NM-PP1
Template:ABSTRACT PUBMED 21116453
About this Structure
3ncg is a 1 chain structure with sequence from Cryptosporidium parvum. Full crystallographic information is available from OCA.
Reference
- Murphy RC, Ojo KK, Larson ET, Castellanos-Gonzalez A, Perera BG, Keyloun KR, Kim JE, Bhandari JG, Muller NR, Verlinde CL, White AC, Merritt EA, Van Voorhis WC, Maly DJ. Discovery of Potent and Selective Inhibitors of Calcium-Dependent Protein Kinase 1 (CDPK1) from C. parvum and T. gondii. ACS Med Chem Lett. 2010 Oct 14;1(7):331-335. PMID:21116453 doi:10.1021/ml100096t
- Ojo KK, Larson ET, Keyloun KR, Castaneda LJ, Derocher AE, Inampudi KK, Kim JE, Arakaki TL, Murphy RC, Zhang L, Napuli AJ, Maly DJ, Verlinde CL, Buckner FS, Parsons M, Hol WG, Merritt EA, Van Voorhis WC. Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors. Nat Struct Mol Biol. 2010 May;17(5):602-7. Epub 2010 May 2. PMID:20436472 doi:10.1038/nsmb.1818
Categories: Calcium/calmodulin-dependent protein kinase | Cryptosporidium parvum | Larson, E T. | MSGPP, Medical Structural Genomics of Pathogenic Protozoa. | Merritt, E A. | Atp-binding | Bumped kinase inhibitor | Calcium-binding | Calmodulin | Medical structural genomics of pathogenic protozoa | Msgpp | Serine/threonine protein kinase | Structural genomic | Transferase | Transferase-transferase inhibitor complex
