3q3k

(Difference between revisions)

Revision as of 08:04, 20 June 2012

3q3k is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Yoshikawa K, Yoshino T, Yokomizo Y, Uoto K, Naito H, Kawakami K, Mochizuki A, Nagata T, Suzuki M, Kanno H, Takemura M, Ohta T. Design, synthesis and SAR of novel ethylenediamine and phenylenediamine derivatives as factor Xa inhibitors. Bioorg Med Chem Lett. 2011 Apr 1;21(7):2133-40. Epub 2011 Feb 1. PMID:21345673 doi:10.1016/j.bmcl.2011.01.132

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 [[Image:3q3k.png|left|200px]]
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 ===Factor Xa in complex with a phenylenediamine derivative===
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