1wco
From Proteopedia
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[[Image:1wco.png|left|200px]] | [[Image:1wco.png|left|200px]] | ||
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{{STRUCTURE_1wco| PDB=1wco | SCENE= }} | {{STRUCTURE_1wco| PDB=1wco | SCENE= }} | ||
| - | === | + | ===The solution structure of the nisin-lipid II complex=== |
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015361862</ref><ref group="xtra">PMID:012056898</ref><ref group="xtra">PMID:010600751</ref><ref group="xtra">PMID:012557191</ref><ref group="xtra">PMID:012580598</ref><references group="xtra"/> |
[[Category: Lactococcus lactis]] | [[Category: Lactococcus lactis]] | ||
[[Category: Monarthropalpus flavus]] | [[Category: Monarthropalpus flavus]] | ||
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[[Category: Nuland, N A.J Van.]] | [[Category: Nuland, N A.J Van.]] | ||
[[Category: Tischenko, E.]] | [[Category: Tischenko, E.]] | ||
| - | [[Category: | + | [[Category: Antimicrobial]] |
| - | [[Category: | + | [[Category: Bacteriocin]] |
| + | [[Category: Food preservative]] | ||
| + | [[Category: Lantibiotic]] | ||
| + | [[Category: Peptide-antibiotic complex]] | ||
[[Category: Pore formation]] | [[Category: Pore formation]] | ||
[[Category: Pyrophosphate cage]] | [[Category: Pyrophosphate cage]] | ||
| + | [[Category: Thioester]] | ||
Revision as of 04:36, 27 June 2012
The solution structure of the nisin-lipid II complex
Template:ABSTRACT PUBMED 15361862
About this Structure
1wco is a 2 chain structure with sequence from Lactococcus lactis and Monarthropalpus flavus. This structure supersedes the now removed PDB entry 1uzt. Full experimental information is available from OCA.
Reference
- Hsu ST, Breukink E, Tischenko E, Lutters MA, de Kruijff B, Kaptein R, Bonvin AM, van Nuland NA. The nisin-lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics. Nat Struct Mol Biol. 2004 Oct;11(10):963-7. Epub 2004 Sep 12. PMID:15361862 doi:10.1038/nsmb830
- Hsu ST, Breukink E, de Kruijff B, Kaptein R, Bonvin AM, van Nuland NA. Mapping the targeted membrane pore formation mechanism by solution NMR: the nisin Z and lipid II interaction in SDS micelles. Biochemistry. 2002 Jun 18;41(24):7670-6. PMID:12056898
- Breukink E, Wiedemann I, van Kraaij C, Kuipers OP, Sahl H, de Kruijff B. Use of the cell wall precursor lipid II by a pore-forming peptide antibiotic. Science. 1999 Dec 17;286(5448):2361-4. PMID:10600751
- Linge JP, Williams MA, Spronk CA, Bonvin AM, Nilges M. Refinement of protein structures in explicit solvent. Proteins. 2003 Feb 15;50(3):496-506. PMID:12557191 doi:10.1002/prot.10299
- Dominguez C, Boelens R, Bonvin AM. HADDOCK: a protein-protein docking approach based on biochemical or biophysical information. J Am Chem Soc. 2003 Feb 19;125(7):1731-7. PMID:12580598 doi:10.1021/ja026939x
Categories: Lactococcus lactis | Monarthropalpus flavus | Bonvin, A M.J J. | Breukink, E. | Hsu, S T.D. | Kaptein, R. | Kruijff, B De. | Lutters, M A.G. | Nuland, N A.J Van. | Tischenko, E. | Antimicrobial | Bacteriocin | Food preservative | Lantibiotic | Peptide-antibiotic complex | Pore formation | Pyrophosphate cage | Thioester
