1dxw
From Proteopedia
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[[Image:1dxw.png|left|200px]] | [[Image:1dxw.png|left|200px]] | ||
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{{STRUCTURE_1dxw| PDB=1dxw | SCENE= }} | {{STRUCTURE_1dxw| PDB=1dxw | SCENE= }} | ||
| - | === | + | ===structure of hetero complex of non structural protein (NS) of hepatitis C virus (HCV) and synthetic peptidic compound=== |
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{{ABSTRACT_PUBMED_10716920}} | {{ABSTRACT_PUBMED_10716920}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[1dxw]] is a | + | [[1dxw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DXW OCA]. |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:010716920</ref><ref group="xtra">PMID:010366511</ref><ref group="xtra">PMID:010366512</ref><ref group="xtra">PMID:009668049</ref><references group="xtra"/> |
| - | [[Category: | + | [[Category: Hepatitis c virus]] |
[[Category: Barbato, G.]] | [[Category: Barbato, G.]] | ||
[[Category: Bazzo, R.]] | [[Category: Bazzo, R.]] | ||
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[[Category: Sambucini, S.]] | [[Category: Sambucini, S.]] | ||
[[Category: Hepatitis c virus]] | [[Category: Hepatitis c virus]] | ||
| - | [[Category: Hydrolase | + | [[Category: Hydrolase-hydrolase inhibitor complex]] |
| - | + | ||
[[Category: Non structural protein]] | [[Category: Non structural protein]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
Revision as of 04:43, 27 June 2012
structure of hetero complex of non structural protein (NS) of hepatitis C virus (HCV) and synthetic peptidic compound
Template:ABSTRACT PUBMED 10716920
About this Structure
1dxw is a 1 chain structure with sequence from Hepatitis c virus. Full experimental information is available from OCA.
Reference
- Barbato G, Cicero DO, Cordier F, Narjes F, Gerlach B, Sambucini S, Grzesiek S, Matassa VG, De Francesco R, Bazzo R. Inhibitor binding induces active site stabilization of the HCV NS3 protein serine protease domain. EMBO J. 2000 Mar 15;19(6):1195-206. PMID:10716920 doi:10.1093/emboj/19.6.1195
- Barbato G, Cicero DO, Nardi MC, Steinkuhler C, Cortese R, De Francesco R, Bazzo R. The solution structure of the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein provides new insights into its activation and catalytic mechanism. J Mol Biol. 1999 Jun 4;289(2):371-84. PMID:10366511 doi:10.1006/jmbi.1999.2745
- Cicero DO, Barbato G, Koch U, Ingallinella P, Bianchi E, Nardi MC, Steinkuhler C, Cortese R, Matassa V, De Francesco R, Pessi A, Bazzo R. Structural characterization of the interactions of optimized product inhibitors with the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein by NMR and modelling studies. J Mol Biol. 1999 Jun 4;289(2):385-96. PMID:10366512 doi:10.1006/jmbi.1999.2746
- Urbani A, Bazzo R, Nardi MC, Cicero DO, De Francesco R, Steinkuhler C, Barbato G. The metal binding site of the hepatitis C virus NS3 protease. A spectroscopic investigation. J Biol Chem. 1998 Jul 24;273(30):18760-9. PMID:9668049
