2c1e
From Proteopedia
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{{STRUCTURE_2c1e| PDB=2c1e | SCENE= }} | {{STRUCTURE_2c1e| PDB=2c1e | SCENE= }} | ||
| - | === | + | ===Crystal structures of caspase-3 in complex with aza-peptide Michael acceptor inhibitors.=== |
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==See Also== | ==See Also== | ||
| - | *[[Caspase]] | + | *[[Caspase|Caspase]] |
==Reference== | ==Reference== | ||
Revision as of 04:44, 27 June 2012
Contents |
Crystal structures of caspase-3 in complex with aza-peptide Michael acceptor inhibitors.
Template:ABSTRACT PUBMED 16970398
About this Structure
2c1e is a 3 chain structure of Caspase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Ekici OD, Li ZZ, Campbell AJ, James KE, Asgian JL, Mikolajczyk J, Salvesen GS, Ganesan R, Jelakovic S, Grutter MG, Powers JC. Design, synthesis, and evaluation of aza-peptide Michael acceptors as selective and potent inhibitors of caspases-2, -3, -6, -7, -8, -9, and -10. J Med Chem. 2006 Sep 21;49(19):5728-49. PMID:16970398 doi:http://dx.doi.org/10.1021/jm0601405
- Shen A, Lupardus PJ, Albrow VE, Guzzetta A, Powers JC, Garcia KC, Bogyo M. Mechanistic and structural insights into the proteolytic activation of Vibrio cholerae MARTX toxin. Nat Chem Biol. 2009 Jul;5(7):469-78. PMID:19465933 doi:10.1038/nchembio.178
