4djz
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
[[Image:4djz.png|left|200px]] | [[Image:4djz.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_4djz", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_4djz| PDB=4djz | SCENE= }} | {{STRUCTURE_4djz| PDB=4djz | SCENE= }} | ||
===Catalytic fragment of masp-1 in complex with its specific inhibitor developed by directed evolution on sgci scaffold=== | ===Catalytic fragment of masp-1 in complex with its specific inhibitor developed by directed evolution on sgci scaffold=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_22511776}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 22511776 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_22511776}} | {{ABSTRACT_PUBMED_22511776}} | ||
Revision as of 04:44, 27 June 2012
Catalytic fragment of masp-1 in complex with its specific inhibitor developed by directed evolution on sgci scaffold
Template:ABSTRACT PUBMED 22511776
About this Structure
4djz is a 6 chain structure with sequence from Homo sapiens and Schistocerca gregaria. Full crystallographic information is available from OCA.
Reference
- Heja D, Harmat V, Fodor K, Wilmanns M, Dobo J, Kekesi KA, Zavodszky P, Gal P, Pal G. Monospecific inhibitors show that both mannan-binding lectin-associated serine protease (MASP)-1 and -2 are essential for lectin pathway activation and reveal structural plasticity of MASP-2. J Biol Chem. 2012 Apr 16. PMID:22511776 doi:10.1074/jbc.M112.354332
