2ydk
From Proteopedia
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{{STRUCTURE_2ydk| PDB=2ydk | SCENE= }} | {{STRUCTURE_2ydk| PDB=2ydk | SCENE= }} | ||
===Discovery of Checkpoint Kinase Inhibitor AZD7762 by Structure Based Design and Optimization of Thiophene Carboxamide Ureas=== | ===Discovery of Checkpoint Kinase Inhibitor AZD7762 by Structure Based Design and Optimization of Thiophene Carboxamide Ureas=== | ||
| + | {{ABSTRACT_PUBMED_22551018}} | ||
==About this Structure== | ==About this Structure== | ||
[[2ydk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YDK OCA]. | [[2ydk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YDK OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022551018</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
Revision as of 04:48, 27 June 2012
Discovery of Checkpoint Kinase Inhibitor AZD7762 by Structure Based Design and Optimization of Thiophene Carboxamide Ureas
Template:ABSTRACT PUBMED 22551018
About this Structure
2ydk is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Oza VB, Ashwell S, Almeida L, Brassil P, Breed J, Deng C, Gero T, Grondine M, Horn C, Ioannidis S, Liu D, Lyne PD, Newcombe N, Pass M, Read J, Ready S, Rowsell S, Su M, Toader D, Vasbinder M, Yu D, Yu Y, Xue Y, Zabludoff S, Janetka J. Discovery of Checkpoint Kinase Inhibitor (S)-5-(3-fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide (AZD7762) by Structure Based Design and Optimization of Thiophene Carboxamide Ureas. J Med Chem. 2012 May 2. PMID:22551018 doi:10.1021/jm300025r
