2cn0

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[[Image:2cn0.png|left|200px]]
[[Image:2cn0.png|left|200px]]
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{{STRUCTURE_2cn0| PDB=2cn0 | SCENE= }}
{{STRUCTURE_2cn0| PDB=2cn0 | SCENE= }}
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===COMPLEX OF RECOMBINANT HUMAN THROMBIN WITH A DESIGNED INHIBITOR===
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===Thrombin-2fluoro===
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{{ABSTRACT_PUBMED_17001711}}
{{ABSTRACT_PUBMED_17001711}}
==About this Structure==
==About this Structure==
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[[2cn0]] is a 3 chain structure of [[Hirudin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CN0 OCA].
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[[2cn0]] is a 3 chain structure of [[Hirudin]] and [[Thrombin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CN0 OCA].
==See Also==
==See Also==
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*[[Hirudin]]
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*[[Hirudin|Hirudin]]
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*[[Thrombin|Thrombin]]
==Reference==
==Reference==
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<ref group="xtra">PMID:17001711</ref><references group="xtra"/>
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<ref group="xtra">PMID:017001711</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Thrombin]]
[[Category: Thrombin]]
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[[Category: Glycoprotein]]
[[Category: Glycoprotein]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Serine protease]]
[[Category: Serine protease]]
[[Category: Serine protease inhibitor complex]]
[[Category: Serine protease inhibitor complex]]

Revision as of 04:49, 27 June 2012

Template:STRUCTURE 2cn0

Contents

Thrombin-2fluoro

Template:ABSTRACT PUBMED 17001711

About this Structure

2cn0 is a 3 chain structure of Hirudin and Thrombin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Hoffmann-Roder A, Schweizer E, Egger J, Seiler P, Obst-Sander U, Wagner B, Kansy M, Banner DW, Diederich F. Mapping the fluorophilicity of a hydrophobic pocket: synthesis and biological evaluation of tricyclic thrombin inhibitors directing fluorinated alkyl groups into the p pocket. ChemMedChem. 2006 Nov;1(11):1205-15. PMID:17001711 doi:10.1002/cmdc.200600124

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