1w9n

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[[Image:1w9n.png|left|200px]]
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{{STRUCTURE_1w9n| PDB=1w9n | SCENE= }}
{{STRUCTURE_1w9n| PDB=1w9n | SCENE= }}
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===ISOLATION AND CHARACTERIZATION OF EPILANCIN 15X, A NOVEL ANTIBIOTIC FROM A CLINICAL STRAIN OF STAPHYLOCOCCUS EPIDERMIDIS===
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===Isolation and characterization of epilancin 15X, a novel lantibiotic from a clinical strain of Staphylococcus epidermidis===
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{{ABSTRACT_PUBMED_15792796}}
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==Reference==
==Reference==
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<ref group="xtra">PMID:15792796</ref><ref group="xtra">PMID:15361862</ref><ref group="xtra">PMID:12056898</ref><ref group="xtra">PMID:12562773</ref><references group="xtra"/>
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<ref group="xtra">PMID:015792796</ref><ref group="xtra">PMID:015361862</ref><ref group="xtra">PMID:012056898</ref><ref group="xtra">PMID:012562773</ref><references group="xtra"/>
[[Category: Staphylococcus epidermidis]]
[[Category: Staphylococcus epidermidis]]
[[Category: Ekkelenkamp, M.]]
[[Category: Ekkelenkamp, M.]]
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[[Category: Nuland, N A.J Van.]]
[[Category: Nuland, N A.J Van.]]
[[Category: Verhoef, J.]]
[[Category: Verhoef, J.]]
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[[Category: Antibacterial]]
[[Category: Antibiotic]]
[[Category: Antibiotic]]
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[[Category: Lanthionine-ring]]
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[[Category: Lanthionine]]
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[[Category: Lantibiotic]]
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[[Category: Thioester]]
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[[Category: Type a lantibiotic]]

Revision as of 04:50, 27 June 2012

Template:STRUCTURE 1w9n

Isolation and characterization of epilancin 15X, a novel lantibiotic from a clinical strain of Staphylococcus epidermidis

Template:ABSTRACT PUBMED 15792796

About this Structure

1w9n is a 1 chain structure with sequence from Staphylococcus epidermidis. Full experimental information is available from OCA.

Reference

  • Ekkelenkamp MB, Hanssen M, Danny Hsu ST, de Jong A, Milatovic D, Verhoef J, van Nuland NA. Isolation and structural characterization of epilancin 15X, a novel lantibiotic from a clinical strain of Staphylococcus epidermidis. FEBS Lett. 2005 Mar 28;579(9):1917-22. PMID:15792796 doi:S0014-5793(05)00240-1
  • Hsu ST, Breukink E, Tischenko E, Lutters MA, de Kruijff B, Kaptein R, Bonvin AM, van Nuland NA. The nisin-lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics. Nat Struct Mol Biol. 2004 Oct;11(10):963-7. Epub 2004 Sep 12. PMID:15361862 doi:10.1038/nsmb830
  • Hsu ST, Breukink E, de Kruijff B, Kaptein R, Bonvin AM, van Nuland NA. Mapping the targeted membrane pore formation mechanism by solution NMR: the nisin Z and lipid II interaction in SDS micelles. Biochemistry. 2002 Jun 18;41(24):7670-6. PMID:12056898
  • Hsu ST, Breukink E, Bierbaum G, Sahl HG, de Kruijff B, Kaptein R, van Nuland NA, Bonvin AM. NMR study of mersacidin and lipid II interaction in dodecylphosphocholine micelles. Conformational changes are a key to antimicrobial activity. J Biol Chem. 2003 Apr 11;278(15):13110-7. Epub 2003 Jan 31. PMID:12562773 doi:10.1074/jbc.M211144200

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