4aqc
From Proteopedia
(Difference between revisions)
m (Protected "4aqc" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | [[Image:4aqc. | + | [[Image:4aqc.png|left|200px]] |
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_4aqc", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_4aqc| PDB=4aqc | SCENE= }} | {{STRUCTURE_4aqc| PDB=4aqc | SCENE= }} | ||
===Triazolopyridine-based Inhibitor of Janus Kinase 2=== | ===Triazolopyridine-based Inhibitor of Janus Kinase 2=== | ||
| + | {{ABSTRACT_PUBMED_22594690}} | ||
==About this Structure== | ==About this Structure== | ||
[[4aqc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AQC OCA]. | [[4aqc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AQC OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022594690</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific protein-tyrosine kinase]] | [[Category: Non-specific protein-tyrosine kinase]] | ||
Revision as of 04:58, 27 June 2012
Triazolopyridine-based Inhibitor of Janus Kinase 2
Template:ABSTRACT PUBMED 22594690
About this Structure
4aqc is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Dugan BJ, Gingrich DE, Mesaros EF, Milkiewicz KL, Curry MA, Zulli AL, Dobrzanski P, Serdikoff C, Jan M, Angeles TS, Albom MS, Mason JL, Aimone LD, Meyer SL, Huang Z, Wells-Knecht KJ, Ator MA, Ruggeri BA, Dorsey BD. A Selective, Orally Bioavailable 1,2,4-Triazolo[1,5-a]pyridine-Based Inhibitor of Janus Kinase 2 for Use in Anticancer Therapy: Discovery of CEP-33779. J Med Chem. 2012 Jun 14;55(11):5243-54. Epub 2012 May 18. PMID:22594690 doi:10.1021/jm300248q
Categories: Homo sapiens | Non-specific protein-tyrosine kinase | Aimone, L D. | Albom, M S. | Angeles, T S. | Ator, M A. | Curry, M A. | Dobrzanski, P. | Dorsey, B D. | Dugan, B J. | Gingrich, D E. | Huang, Z. | Jan, M. | Mason, J L. | Mesaros, E F. | Meyer, S L. | Milkiewicz, K L. | Ruggeri, B A. | Serdikoff, C. | Wells-Knecht, K J. | Zulli, A L. | Atp-binding | Transferase
