2rgf
From Proteopedia
(New page: 200px<br /> <applet load="2rgf" size="450" color="white" frame="true" align="right" spinBox="true" caption="2rgf" /> '''RBD OF RAL GUANOSINE-NUCLEOTIDE EXCHANGE FA...) |
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'''RBD OF RAL GUANOSINE-NUCLEOTIDE EXCHANGE FACTOR (PROTEIN), NMR, 10 STRUCTURES'''<br /> | '''RBD OF RAL GUANOSINE-NUCLEOTIDE EXCHANGE FACTOR (PROTEIN), NMR, 10 STRUCTURES'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2RGF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http:// | + | 2RGF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RGF OCA]. |
==Reference== | ==Reference== | ||
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[[Category: rbd]] | [[Category: rbd]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Feb 15 17:42:07 2008'' |
Revision as of 15:42, 15 February 2008
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RBD OF RAL GUANOSINE-NUCLEOTIDE EXCHANGE FACTOR (PROTEIN), NMR, 10 STRUCTURES
Overview
The solution structure of the Ras-binding domain (RBD) of Ral, guanine-nucleotide exchange factor RalGEF was solved by NMR spectroscopy., The overall structure is similar to that of Raf-RBD, another effector of, Ras, although the sequence identity is only 13%. 15N chemical shifts, changes in the complex of RalGEF-RBD with Ras indicate an interaction, similar to the intermolecular beta-sheet observed for the complex between, Ras and Raf-RBD.
About this Structure
2RGF is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Structure of the Ras-binding domain of RalGEF and implications for Ras binding and signalling., Geyer M, Herrmann C, Wohlgemuth S, Wittinghofer A, Kalbitzer HR, Nat Struct Biol. 1997 Sep;4(9):694-9. PMID:9302994
Page seeded by OCA on Fri Feb 15 17:42:07 2008
Categories: Homo sapiens | Single protein | Geyer, M. | Herrmann, C. | Kalbitzer, H.R. | Wittinghofer, A. | Ralgds | Ralgef | Ras | Ras-binding domain | Rbd
