4eft

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-	'''Unreleased structure'''	+	[[Image:4eft.jpg|left|200px]]
-	The entry 4eft is ON HOLD	+	{{STRUCTURE_4eft| PDB=4eft | SCENE= }}
-	Authors: Musil, D., Lehmann, M., Graedler, U., Buchstaller, H.-P.	+	===Hsp90 Alpha N-terminal Domain in Complex with an Inhibitor 3-Cyclohexyl-2-(6-hydroxy-1H-indazol-3-yl)-propionitrile===
-	Description: Hsp90 Alpha N-terminal Domain in Complex with an Inhibitor 3-Cyclohexyl-2-(6-hydroxy-1H-indazol-3-yl)-propionitrile	+	{{ABSTRACT_PUBMED_22632933}}
		+
		+	==About this Structure==
		+	[[4eft]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EFT OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022632933</ref><references group="xtra"/>
		+	[[Category: Homo sapiens]]
		+	[[Category: Buchstaller, H P.]]
		+	[[Category: Graedler, U.]]
		+	[[Category: Lehmann, M.]]
		+	[[Category: Musil, D.]]
		+	[[Category: Atp binding]]
		+	[[Category: Chaperone-chaperone inhibitor complex]]

---

Revision as of 05:45, 27 June 2012

Template:STRUCTURE 4eft

Hsp90 Alpha N-terminal Domain in Complex with an Inhibitor 3-Cyclohexyl-2-(6-hydroxy-1H-indazol-3-yl)-propionitrile

Template:ABSTRACT PUBMED 22632933

About this Structure

4eft is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Buchstaller HP, Eggenweiler HM, Sirrenberg C, Gradler U, Musil D, Hoppe E, Zimmermann A, Schwartz H, Marz J, Bomke J, Wegener A, Wolf M. Fragment-based discovery of hydroxy-indazole-carboxamides as novel small molecule inhibitors of Hsp90. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4396-403. Epub 2012 May 5. PMID:22632933 doi:10.1016/j.bmcl.2012.04.121