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4eo6

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m (Protected "4eo6" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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[[Image:4eo6.jpg|left|200px]]
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The entry 4eo6 is ON HOLD
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{{STRUCTURE_4eo6| PDB=4eo6 | SCENE= }}
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Authors: Appleby, T.C., Canales, E., Watkins, W.J.
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===HCV NS5B polymerase inhibitors: Tri-substituted acylhydrazines as tertiary amide bioisosteres===
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Description: HCV NS5B polymerase inhibitors: Tri-substituted acylhydrazines as tertiary amide bioisosteres
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{{ABSTRACT_PUBMED_22664130}}
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==About this Structure==
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[[4eo6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EO6 OCA].
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==Reference==
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<ref group="xtra">PMID:022664130</ref><references group="xtra"/>
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[[Category: RNA-directed RNA polymerase]]
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[[Category: Viruses]]
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[[Category: Appleby, T C.]]
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[[Category: Canales, E.]]
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[[Category: Watkins, W J.]]
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[[Category: Hcv]]
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[[Category: Ns5b]]
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[[Category: Polymerase inhibitor]]
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[[Category: Rna]]
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[[Category: Rna polymerase]]
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[[Category: Rna-dependent rna polymerase]]
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[[Category: Thumb site 2 inhibitor]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 05:46, 27 June 2012

Image:4eo6.jpg

Template:STRUCTURE 4eo6

HCV NS5B polymerase inhibitors: Tri-substituted acylhydrazines as tertiary amide bioisosteres

Template:ABSTRACT PUBMED 22664130

About this Structure

4eo6 is a 2 chain structure with sequence from Viruses. Full crystallographic information is available from OCA.

Reference

  • Canales E, Carlson JS, Appleby T, Fenaux M, Lee J, Tian Y, Tirunagari N, Wong M, Watkins WJ. Tri-substituted acylhydrazines as tertiary amide bioisosteres: HCV NS5B polymerase inhibitors. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4288-92. Epub 2012 May 17. PMID:22664130 doi:10.1016/j.bmcl.2012.05.025

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