4eo8

(Difference between revisions)

Revision as of 05:49, 27 June 2012

4eo8 is a 2 chain structure with sequence from Viruses. Full crystallographic information is available from OCA.

Canales E, Carlson JS, Appleby T, Fenaux M, Lee J, Tian Y, Tirunagari N, Wong M, Watkins WJ. Tri-substituted acylhydrazines as tertiary amide bioisosteres: HCV NS5B polymerase inhibitors. Bioorg Med Chem Lett. 2012 Jul 1;22(13):4288-92. Epub 2012 May 17. PMID:22664130 doi:10.1016/j.bmcl.2012.05.025

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-'''Unreleased structure'''
+[[Image:4eo8.jpg|left|200px]]
-The entry 4eo8 is ON HOLD
+{{STRUCTURE_4eo8|  PDB=4eo8  |  SCENE=  }}
-Authors: Appleby, T.C., Canales, E., Watkins, W.J.
+===HCV NS5B polymerase inhibitors: Tri-substituted acylhydrazines as tertiary amide bioisosteres===
-Description: HCV NS5B polymerase inhibitors: Tri-substituted acylhydrazines as tertiary amide bioisosteres
+{{ABSTRACT_PUBMED_22664130}}
+==About this Structure==
+[[4eo8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Viruses Viruses]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EO8 OCA].
+==Reference==
+<ref group="xtra">PMID:022664130</ref><references group="xtra"/>
+[[Category: RNA-directed RNA polymerase]]
+[[Category: Viruses]]
+[[Category: Appleby, T C.]]
+[[Category: Canales, E.]]
+[[Category: Watkins, W J.]]
+[[Category: Hcv]]
+[[Category: Ns5b]]
+[[Category: Polymerase inhibitor]]
+[[Category: Rna]]
+[[Category: Rna polymerase]]
+[[Category: Rna-dependent rna polymerase]]
+[[Category: Thumb site 2 inhibitor]]
+[[Category: Transferase-transferase inhibitor complex]]