Hox protein

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=Hox-DNA Recognition=
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=Hox Proteins Specifically Recognize the Sequence-Dependent Shape of the Minor Groove=
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==Biological Role of Hox Proteins=
[[Image:Hox-intro.jpg|thumb|left|200px|Crystal structure of Exd-Scr-DNA ternary complex; PDB ID# 2R5Z (cite).]]
[[Image:Hox-intro.jpg|thumb|left|200px|Crystal structure of Exd-Scr-DNA ternary complex; PDB ID# 2R5Z (cite).]]

Revision as of 04:55, 2 July 2012

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Hox Proteins Specifically Recognize the Sequence-Dependent Shape of the Minor Groove

=Biological Role of Hox Proteins

Crystal structure of Exd-Scr-DNA ternary complex; PDB ID# 2R5Z (cite).
Crystal structure of Exd-Scr-DNA ternary complex; PDB ID# 2R5Z (cite).

Important for embryonic development across species. Recognize DNA with high binding specificity. Eight Drosophila Hox proteins. Bind with a co-factor. Shows crystal structure of Scr-Exd-DNA ternary complex.

Latent specificity of Hox proteins (cite).
Latent specificity of Hox proteins (cite).
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Image:Slattery-etal-Figure6.jpg
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