1gvi

From Proteopedia

Revision as of 11:23, 30 October 2007

THERMUS MALTOGENIC AMYLASE IN COMPLEX WITH BETA-CD

Overview

Over 20 enzymes denoted as cyclomaltodextrinase, maltogenic amylase, or, neopullulanase that share 40-86% sequence identity with each other are, found in public data bases. These enzymes are distinguished from typical, alpha-amylases by containing a novel N-terminal domain and exhibiting, preferential substrate specificities for cyclomaltodextrins (CDs) over, starch. In this research field, a great deal of confusion exists regarding, the features distinguishing the three groups of enzymes from one another., Although a different enzyme code has been assigned to each of the three, different enzyme names, even a single differentiating enzymatic property, has not been documented in the literature. On the other hand, an, outstanding question related to this issue concerns the structural basis, ... [(full description)]

About this Structure

1GVI is a [Single protein] structure of sequence from [Thermus sp.] with BCD as [ligand]. Structure known Active Site: AC1. Full crystallographic information is available from [OCA].

Reference

Cyclomaltodextrinase, neopullulanase, and maltogenic amylase are nearly indistinguishable from each other., Lee HS, Kim MS, Cho HS, Kim JI, Kim TJ, Choi JH, Park C, Lee HS, Oh BH, Park KH, J Biol Chem. 2002 Jun 14;277(24):21891-7. Epub 2002 Mar 28. PMID:11923309

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