4fob

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Revision as of 05:28, 27 June 2012 (edit) OCA (Talk | contribs) m (Protected "4fob" [edit=sysop:move=sysop]) ← Previous diff		Revision as of 08:08, 11 July 2012 (edit) (undo) OCA (Talk | contribs) Next diff →
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-	'''Unreleased structure'''	+	[[Image:4fob.jpg|left|200px]]
-	The entry 4fob is ON HOLD	+	{{STRUCTURE_4fob| PDB=4fob | SCENE= }}
-	Authors: Whittington, D.A., Epstein, L.F., Chen, H.	+	===Crystal structure of human anaplastic lymphoma kinase in complex with acyliminobenzimidazole inhibitor 1===
-	Description: Crystal structure of human anaplastic lymphoma kinase in complex with acyliminobenzimidazole inhibitor 1	+	{{ABSTRACT_PUBMED_22734674}}
		+
		+	==About this Structure==
		+	[[4fob]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FOB OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022734674</ref><references group="xtra"/>
		+	[[Category: Homo sapiens]]
		+	[[Category: Receptor protein-tyrosine kinase]]
		+	[[Category: Chen, H.]]
		+	[[Category: Epstein, L F.]]
		+	[[Category: Whittington, D A.]]
		+	[[Category: Cd246]]
		+	[[Category: Crizotinib]]
		+	[[Category: Eml4-alk]]
		+	[[Category: In situ proteolysis]]
		+	[[Category: Inhibitor]]
		+	[[Category: Neuroblastoma]]
		+	[[Category: Npm-alk]]
		+	[[Category: Phosphotransferase]]
		+	[[Category: Receptor tyrosine kinase]]
		+	[[Category: Transferase-inhibitor complex]]

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Revision as of 08:08, 11 July 2012

Template:STRUCTURE 4fob

Crystal structure of human anaplastic lymphoma kinase in complex with acyliminobenzimidazole inhibitor 1

Template:ABSTRACT PUBMED 22734674

About this Structure

4fob is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Lewis RT, Bode CM, Choquette D, Potashman M, Romero K, Stellwagen JC, Teffera Y, Moore E, Whittington DA, Chen H, Epstein LF, Emkey R, Andrews PS, Yu V, Saffran DC, Xu M, Drew AE, Merkel P, Szilvassy S, Brake RL. The discovery and optimization of a novel class of potent, selective and orally bioavailable Anaplastic Lymphoma Kinase (ALK) Inhibitors with potential utility for the treatment of cancer. J Med Chem. 2012 Jun 26. PMID:22734674 doi:10.1021/jm3005866