4dmx

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'''Unreleased structure'''
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[[Image:4dmx.jpg|left|200px]]
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The entry 4dmx is ON HOLD until Paper Publication
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{{STRUCTURE_4dmx| PDB=4dmx | SCENE= }}
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Authors: Dossetter, A.G., Beeley, H., Bowyer, J., Cook, C.R., Crawford, J.J., Finlayson, J.E., Heron, N.M., Heyes, C., Highton, A.J., Hudson, J.A., Kenny, P.W, Martin, S., MacFaul, P.A., McGuire, T.M., Gutierrez, P.M., Morley, A.D., Morris, J.J., Page, K.M., Rosenbrier Ribeiro, L., Sawney, H., Steinbacher, S., Krapp, S., Jestel, A., Smith, C., Vickers, M.
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===Cathepsin K inhibitor===
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Description: Cathepsin K inhibitor
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{{ABSTRACT_PUBMED_22742641}}
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==About this Structure==
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[[4dmx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DMX OCA].
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==Reference==
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<ref group="xtra">PMID:022742641</ref><references group="xtra"/>
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[[Category: Cathepsin K]]
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[[Category: Homo sapiens]]
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[[Category: Beeley, H.]]
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[[Category: Bowyer, J.]]
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[[Category: Cook, C R.]]
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[[Category: Crawford, J J.]]
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[[Category: Dossetter, A G.]]
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[[Category: Finlayson, J E.]]
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[[Category: Gutierrez, P M.]]
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[[Category: Heron, N M.]]
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[[Category: Heyes, C.]]
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[[Category: Highton, A J.]]
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[[Category: Hudson, J A.]]
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[[Category: Jestel, A.]]
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[[Category: Kenny, P W]]
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[[Category: Krapp, S.]]
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[[Category: MacFaul, P A.]]
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[[Category: Martin, S.]]
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[[Category: McGuire, T M.]]
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[[Category: Morley, A D.]]
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[[Category: Morris, J J.]]
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[[Category: Page, K M.]]
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[[Category: Ribeiro, L Rosenbrier.]]
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[[Category: Sawney, H.]]
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[[Category: Smith, C.]]
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[[Category: Steinbacher, S.]]
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[[Category: Vickers, M.]]
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[[Category: Cathepsin k inhibitor]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Osteoarthritis]]

Revision as of 08:16, 11 July 2012

Image:4dmx.jpg

Template:STRUCTURE 4dmx

Cathepsin K inhibitor

Template:ABSTRACT PUBMED 22742641

About this Structure

4dmx is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Dossetter A, Beeley H, Bowyer J, Cook CR, Crawford JJ, Finlayson JE, Heron NM, Heyes C, Highton AJ, Hudson JA, Jestel A, Kenny PW, Krapp S, Martin S, Macfaul PA, McGuire TM, Morentin-Gutierrez P, Morley AD, Morris JJ, Page KM, Rosenbrier-Ribeiro L, Sawney H, Steinbacher S, Smith C, Vickers M. (1R,2R)-N-(1-cyanocyclopropyl)-2-(6-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indole -2-carbonyl)cyclohexanecarboxamide (AZD4996): A potent and highly selective Cathepsin K inhibitor for the treatment of osteoarthritis. J Med Chem. 2012 Jun 28. PMID:22742641 doi:10.1021/jm3007257

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OCA

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