4dii
From Proteopedia
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| - | + | [[Image:4dii.jpg|left|200px]] | |
| - | + | {{STRUCTURE_4dii| PDB=4dii | SCENE= }} | |
| - | + | ===X-ray structure of the complex between human alpha thrombin and thrombin binding aptamer in the presence of potassium ions=== | |
| - | + | {{ABSTRACT_PUBMED_22669903}} | |
| + | |||
| + | ==About this Structure== | ||
| + | [[4dii]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DII OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022669903</ref><ref group="xtra">PMID:021715374</ref><ref group="xtra">PMID:008102368</ref><ref group="xtra">PMID:015299700</ref><references group="xtra"/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Thrombin]] | ||
| + | [[Category: Krauss, I Russo.]] | ||
| + | [[Category: Mazzarella, L.]] | ||
| + | [[Category: Merlino, A.]] | ||
| + | [[Category: Sica, F.]] | ||
| + | [[Category: Aptamer]] | ||
| + | [[Category: Blood]] | ||
| + | [[Category: Blood coagulation]] | ||
| + | [[Category: Dna aptamer]] | ||
| + | [[Category: G-quadruplex]] | ||
| + | [[Category: Hydrolase-hydrolase inhibitor-dna complex]] | ||
| + | [[Category: Protein-dna complex]] | ||
| + | [[Category: Serine protease]] | ||
| + | [[Category: Serine protease fold]] | ||
Revision as of 05:22, 18 July 2012
X-ray structure of the complex between human alpha thrombin and thrombin binding aptamer in the presence of potassium ions
Template:ABSTRACT PUBMED 22669903
About this Structure
4dii is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Russo Krauss I, Merlino A, Randazzo A, Novellino E, Mazzarella L, Sica F. High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity. Nucleic Acids Res. 2012 Jun 4. PMID:22669903 doi:10.1093/nar/gks512
- Russo Krauss I, Merlino A, Giancola C, Randazzo A, Mazzarella L, Sica F. Thrombin-aptamer recognition: a revealed ambiguity. Nucleic Acids Res. 2011 Sep 1;39(17):7858-67. Epub 2011 Jun 28. PMID:21715374 doi:10.1093/nar/gkr522
- Padmanabhan K, Padmanabhan KP, Ferrara JD, Sadler JE, Tulinsky A. The structure of alpha-thrombin inhibited by a 15-mer single-stranded DNA aptamer. J Biol Chem. 1993 Aug 25;268(24):17651-4. PMID:8102368
- Padmanabhan K, Tulinsky A. An ambiguous structure of a DNA 15-mer thrombin complex. Acta Crystallogr D Biol Crystallogr. 1996 Mar 1;52(Pt 2):272-82. PMID:15299700 doi:10.1107/S0907444995013977
