4dhf

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-	'''Unreleased structure'''	+	[[Image:4dhf.jpg|left|200px]]
-	The entry 4dhf is ON HOLD until Paper Publication	+	{{STRUCTURE_4dhf| PDB=4dhf | SCENE= }}
-	Authors: Silvian, L., Marcotte, D.J.	+	===Structure of Aurora A mutant bound to Biogenidec cpd 15===
-	Description: Structure of Aurora A mutant bound to Biogenidec cpd 15	+	{{ABSTRACT_PUBMED_22607669}}
		+
		+	==About this Structure==
		+	[[4dhf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DHF OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022607669</ref><references group="xtra"/>
		+	[[Category: Homo sapiens]]
		+	[[Category: Non-specific serine/threonine protein kinase]]
		+	[[Category: Marcotte, D J.]]
		+	[[Category: Silvian, L.]]
		+	[[Category: Phosphorylation]]
		+	[[Category: Ser/thr kinase mitotic kinase pyrazolopyrimidine]]
		+	[[Category: Tpx2]]
		+	[[Category: Transferase-transferase inhibitor complex]]

---

Revision as of 05:24, 18 July 2012

Template:STRUCTURE 4dhf

Structure of Aurora A mutant bound to Biogenidec cpd 15

Template:ABSTRACT PUBMED 22607669

About this Structure

4dhf is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Le Brazidec JY, Pasis A, Tam B, Boykin C, Wang D, Marcotte DJ, Claassen G, Chong JH, Chao J, Fan J, Nguyen K, Silvian L, Ling L, Zhang L, Choi M, Teng M, Pathan N, Zhao S, Li T, Taveras A. Structure-based design of 2,6,7-trisubstituted-7H-pyrrolo[2,3-d]pyrimidines as Aurora kinases inhibitors. Bioorg Med Chem Lett. 2012 Jun 15;22(12):4033-7. Epub 2012 Apr 25. PMID:22607669 doi:10.1016/j.bmcl.2012.04.085