4dg1
From Proteopedia
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{{STRUCTURE_4dg1| PDB=4dg1 | SCENE= }} | {{STRUCTURE_4dg1| PDB=4dg1 | SCENE= }} | ||
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===Crystal structure of HIV-1 reverse transcriptase (RT) with polymorphism mutation K172A and K173A=== | ===Crystal structure of HIV-1 reverse transcriptase (RT) with polymorphism mutation K172A and K173A=== | ||
| + | {{ABSTRACT_PUBMED_22761416}} | ||
==About this Structure== | ==About this Structure== | ||
[[4dg1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DG1 OCA]. | [[4dg1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DG1 OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022761416</ref><references group="xtra"/> | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: Kirby, K A.]] | [[Category: Kirby, K A.]] | ||
Revision as of 06:01, 25 July 2012
Crystal structure of HIV-1 reverse transcriptase (RT) with polymorphism mutation K172A and K173A
Template:ABSTRACT PUBMED 22761416
About this Structure
4dg1 is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
- Hachiya A, Marchand B, Kirby KA, Michailidis E, Tu X, Palczewski K, Ong YT, Li Z, Griffin DT, Schuckmann MM, Tanuma J, Oka S, Singh K, Kodama EN, Sarafianos SG. HIV-1 reverse transcriptase (RT) polymorphism 172K, suppresses the effect of clinically relevant drug resistance mutations to both nucleoside and nonnucleoside RT inhibitors. J Biol Chem. 2012 Jul 2. PMID:22761416 doi:10.1074/jbc.M112.351551
Categories: Human immunodeficiency virus 1 | Kirby, K A. | Marchand, B. | Sarafianos, S G. | Tu, X. | Aid | Azt | Azt excision | Azt unblocking | Dna polymerase | Efavirenz | Hetero dimer | Hiv | Nevirapine | Nnrti | Nonnucleoside inhibitor | Nrti | Nucleoside inhibitor | P51/p66 | Polymorphism 172k | Resistance mutation | Reverse transcriptase | Ribonuclease h | Right-hand configuration | Rna-directed dna polymerase | Rnase h domain | Transferase
