3ras
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
[[Image:3ras.png|left|200px]] | [[Image:3ras.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3ras", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3ras| PDB=3ras | SCENE= }} | {{STRUCTURE_3ras| PDB=3ras | SCENE= }} | ||
===Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) complexed with a lipophilic phosphonate inhibitor=== | ===Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) complexed with a lipophilic phosphonate inhibitor=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_21561155}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 21561155 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_21561155}} | {{ABSTRACT_PUBMED_21561155}} | ||
| Line 33: | Line 22: | ||
[[Category: Isoprene biosynthesis]] | [[Category: Isoprene biosynthesis]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
| - | [[Category: Oxidoreductase-inhibitor complex]] | + | [[Category: Oxidoreductase-oxidoreductase inhibitor complex]] |
Revision as of 06:13, 25 July 2012
Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) complexed with a lipophilic phosphonate inhibitor
Template:ABSTRACT PUBMED 21561155
About this Structure
3ras is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Deng L, Diao J, Chen P, Pujari V, Yao Y, Cheng G, Crick DC, Prasad BV, Song Y. Inhibition of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase by Lipophilic Phosphonates: SAR, QSAR and Crystallographic Studies. J Med Chem. 2011 May 11. PMID:21561155 doi:10.1021/jm200363d
