4epv
From Proteopedia
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===Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-mediated Activation=== | ===Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-mediated Activation=== | ||
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Revision as of 06:13, 25 July 2012
Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-mediated Activation
Template:ABSTRACT PUBMED 22566140
About this Structure
4epv is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Sun Q, Burke JP, Phan J, Burns MC, Olejniczak ET, Waterson AG, Lee T, Rossanese OW, Fesik SW. Discovery of Small Molecules that Bind to K-Ras and Inhibit Sos-Mediated Activation. Angew Chem Int Ed Engl. 2012 May 8. doi: 10.1002/anie.201201358. PMID:22566140 doi:10.1002/anie.201201358
Categories: Homo sapiens | Small monomeric GTPase | Burke, J P. | Burns, M C. | Fesik, S W. | Lee, T. | Olejniczak, E T. | Phan, J. | Rossanese, O W. | Sun, Q. | Waterson, A G. | Binder | Cytosol | Hydrolase | Inhibitor of sos-mediated activation | Pi3k | Raf | Ral | Signaling transduction | Small gtpase | So
