3vsx

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-	'''Unreleased structure'''	+	[[Image:3vsx.jpg|left|200px]]
-	The entry 3vsx is ON HOLD until Paper Publication	+	{{STRUCTURE_3vsx| PDB=3vsx | SCENE= }}
-	Authors: Takahashi, M., Hanzawa, H.	+	===Human renin in complex with compound 18===
-	Description: Human renin in complex with compound 18	+	{{ABSTRACT_PUBMED_22726934}}
		+
		+	==About this Structure==
		+	[[3vsx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VSX OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022726934</ref><references group="xtra"/>
		+	[[Category: Homo sapiens]]
		+	[[Category: Renin]]
		+	[[Category: Hanzawa, H.]]
		+	[[Category: Takahashi, M.]]
		+	[[Category: Aspartyl protease]]
		+	[[Category: Hydrolase-hydrolase inhibitor complex]]
		+	[[Category: Hypertension]]
		+	[[Category: Inhibitor]]
		+	[[Category: Ra]]

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Revision as of 07:12, 25 July 2012

Template:STRUCTURE 3vsx

Human renin in complex with compound 18

Template:ABSTRACT PUBMED 22726934

About this Structure

3vsx is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Nakamura Y, Sugita C, Meguro M, Miyazaki S, Tamaki K, Takahashi M, Nagai Y, Nagayama T, Kato M, Suemune H, Nishi T. Design and optimization of novel (2S,4S,5S)-5-amino-6-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1-yl)-4-hydroxy-2-isop ropylhexanamides as renin inhibitors. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4561-6. Epub 2012 Jun 4. PMID:22726934 doi:10.1016/j.bmcl.2012.05.092