3iit
From Proteopedia
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{{STRUCTURE_3iit| PDB=3iit | SCENE= }} | {{STRUCTURE_3iit| PDB=3iit | SCENE= }} | ||
===Factor XA in complex with a cis-1,2-diaminocyclohexane derivative=== | ===Factor XA in complex with a cis-1,2-diaminocyclohexane derivative=== | ||
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{{ABSTRACT_PUBMED_19900814}} | {{ABSTRACT_PUBMED_19900814}} | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[3iit]] is a 2 chain structure of [[Factor Xa]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IIT OCA]. | |
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+ | ==See Also== | ||
+ | *[[Factor Xa|Factor Xa]] | ||
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019900814</ref><references group="xtra"/> |
[[Category: Coagulation factor Xa]] | [[Category: Coagulation factor Xa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Serine protease]] | [[Category: Serine protease]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 4 09:06:20 2010'' |
Revision as of 09:26, 25 July 2012
Contents |
Factor XA in complex with a cis-1,2-diaminocyclohexane derivative
Template:ABSTRACT PUBMED 19900814
About this Structure
3iit is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Yoshikawa K, Kobayashi S, Nakamoto Y, Haginoya N, Komoriya S, Yoshino T, Nagata T, Mochizuki A, Watanabe K, Suzuki M, Kanno H, Ohta T. Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part II: exploration of 6-6 fused rings as alternative S1 moieties. Bioorg Med Chem. 2009 Dec 15;17(24):8221-33. Epub 2009 Oct 17. PMID:19900814 doi:10.1016/j.bmc.2009.10.024
Categories: Coagulation factor Xa | Homo sapiens | Suzuki, M. | Blood coagulation | Blood coagulation factor | Calcium-binding | Cleavage on pair of basic residue | Disulfide bond | Egf-like domain | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Hydroxylation | Plasma | Protease | Protein inhibitor complex | Secreted | Serine protease | Zymogen