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1sa4
From Proteopedia
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[[Image:1sa4.png|left|200px]] | [[Image:1sa4.png|left|200px]] | ||
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{{STRUCTURE_1sa4| PDB=1sa4 | SCENE= }} | {{STRUCTURE_1sa4| PDB=1sa4 | SCENE= }} | ||
===human protein farnesyltransferase complexed with FPP and R115777=== | ===human protein farnesyltransferase complexed with FPP and R115777=== | ||
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{{ABSTRACT_PUBMED_15170324}} | {{ABSTRACT_PUBMED_15170324}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1sa4]] is a 2 chain structure of [[Farnesyltransferase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SA4 OCA]. | |
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| + | ==See Also== | ||
| + | *[[Farnesyltransferase|Farnesyltransferase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015170324</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein farnesyltransferase]] | [[Category: Protein farnesyltransferase]] | ||
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[[Category: Ra]] | [[Category: Ra]] | ||
[[Category: Tipifarnib]] | [[Category: Tipifarnib]] | ||
| + | [[Category: Transferase]] | ||
[[Category: Tumor regression]] | [[Category: Tumor regression]] | ||
[[Category: Zarnestra]] | [[Category: Zarnestra]] | ||
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Revision as of 09:28, 25 July 2012
Contents |
human protein farnesyltransferase complexed with FPP and R115777
Template:ABSTRACT PUBMED 15170324
About this Structure
1sa4 is a 2 chain structure of Farnesyltransferase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Reid TS, Beese LS. Crystal structures of the anticancer clinical candidates R115777 (Tipifarnib) and BMS-214662 complexed with protein farnesyltransferase suggest a mechanism of FTI selectivity. Biochemistry. 2004 Jun 8;43(22):6877-84. PMID:15170324 doi:10.1021/bi049723b
Categories: Homo sapiens | Protein farnesyltransferase | Beese, L S. | Reid, T S. | Caax | Cancer | Clinical candidate | Farnesyl transferase | Farnesyltransferase | Ftase | Fti | Inhibitor | Lipid modification | Protein prenylation | R115777 | Ra | Tipifarnib | Transferase | Tumor regression | Zarnestra
