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1sa4
From Proteopedia
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Revision as of 09:28, 25 July 2012
Contents |
human protein farnesyltransferase complexed with FPP and R115777
Template:ABSTRACT PUBMED 15170324
About this Structure
1sa4 is a 2 chain structure of Farnesyltransferase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Reid TS, Beese LS. Crystal structures of the anticancer clinical candidates R115777 (Tipifarnib) and BMS-214662 complexed with protein farnesyltransferase suggest a mechanism of FTI selectivity. Biochemistry. 2004 Jun 8;43(22):6877-84. PMID:15170324 doi:10.1021/bi049723b
Categories: Homo sapiens | Protein farnesyltransferase | Beese, L S. | Reid, T S. | Caax | Cancer | Clinical candidate | Farnesyl transferase | Farnesyltransferase | Ftase | Fti | Inhibitor | Lipid modification | Protein prenylation | R115777 | Ra | Tipifarnib | Transferase | Tumor regression | Zarnestra
