2b4s
From Proteopedia
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===Crystal structure of a complex between PTP1B and the insulin receptor tyrosine kinase=== | ===Crystal structure of a complex between PTP1B and the insulin receptor tyrosine kinase=== | ||
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{{ABSTRACT_PUBMED_16271887}} | {{ABSTRACT_PUBMED_16271887}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Leprechaunism OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Rabson-Mendenhall syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[2b4s]] is a 4 chain structure of [[Proten tyrosine phosphatase]] and [[Tyrosine phosphatase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B4S OCA]. | |
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| + | ==See Also== | ||
| + | *[[Proten tyrosine phosphatase|Proten tyrosine phosphatase]] | ||
| + | *[[Tyrosine phosphatase|Tyrosine phosphatase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:016271887</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein-tyrosine-phosphatase]] | [[Category: Protein-tyrosine-phosphatase]] | ||
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[[Category: Hubbard, S R.]] | [[Category: Hubbard, S R.]] | ||
[[Category: Li, S.]] | [[Category: Li, S.]] | ||
| + | [[Category: Hydrolase-transferase complex]] | ||
[[Category: Hydrolase/transferase]] | [[Category: Hydrolase/transferase]] | ||
[[Category: Phosphorylation]] | [[Category: Phosphorylation]] | ||
[[Category: Tyrosine protein kinase]] | [[Category: Tyrosine protein kinase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 10:03:43 2009'' | ||
Revision as of 09:33, 25 July 2012
Contents |
Crystal structure of a complex between PTP1B and the insulin receptor tyrosine kinase
Template:ABSTRACT PUBMED 16271887
About this Structure
2b4s is a 4 chain structure of Proten tyrosine phosphatase and Tyrosine phosphatase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Li S, Depetris RS, Barford D, Chernoff J, Hubbard SR. Crystal structure of a complex between protein tyrosine phosphatase 1B and the insulin receptor tyrosine kinase. Structure. 2005 Nov;13(11):1643-51. PMID:16271887 doi:10.1016/j.str.2005.07.019
