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3g4a

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[[Image:3g4a.png|left|200px]]
[[Image:3g4a.png|left|200px]]
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{{STRUCTURE_3g4a| PDB=3g4a | SCENE= }}
{{STRUCTURE_3g4a| PDB=3g4a | SCENE= }}
===Crystal structure of flavine dependant thymidylate synthase S88A mutant from Thermotoga maritima at 1.95 angstrom resolution===
===Crystal structure of flavine dependant thymidylate synthase S88A mutant from Thermotoga maritima at 1.95 angstrom resolution===
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{{ABSTRACT_PUBMED_19370033}}
{{ABSTRACT_PUBMED_19370033}}
==About this Structure==
==About this Structure==
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[[3g4a]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G4A OCA].
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[[3g4a]] is a 4 chain structure of [[Thymidylate synthase]] with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G4A OCA].
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==See Also==
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*[[Thymidylate synthase|Thymidylate synthase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:19370033</ref><ref group="xtra">PMID:12791256</ref><ref group="xtra">PMID:15301527</ref><references group="xtra"/>
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<ref group="xtra">PMID:019370033</ref><ref group="xtra">PMID:012791256</ref><ref group="xtra">PMID:015301527</ref><references group="xtra"/>
[[Category: Thermotoga maritima msb8]]
[[Category: Thermotoga maritima msb8]]
[[Category: Kohen, A.]]
[[Category: Kohen, A.]]

Revision as of 09:39, 25 July 2012

Template:STRUCTURE 3g4a

Contents

Crystal structure of flavine dependant thymidylate synthase S88A mutant from Thermotoga maritima at 1.95 angstrom resolution

Template:ABSTRACT PUBMED 19370033

About this Structure

3g4a is a 4 chain structure of Thymidylate synthase with sequence from Thermotoga maritima msb8. Full crystallographic information is available from OCA.

See Also

Reference

  • Koehn EM, Fleischmann T, Conrad JA, Palfey BA, Lesley SA, Mathews II, Kohen A. An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene. Nature. 2009 Apr 16;458(7240):919-23. PMID:19370033 doi:10.1038/nature07973
  • Mathews II, Deacon AM, Canaves JM, McMullan D, Lesley SA, Agarwalla S, Kuhn P. Functional analysis of substrate and cofactor complex structures of a thymidylate synthase-complementing protein. Structure. 2003 Jun;11(6):677-90. PMID:12791256
  • Agrawal N, Lesley SA, Kuhn P, Kohen A. Mechanistic studies of a flavin-dependent thymidylate synthase. Biochemistry. 2004 Aug 17;43(32):10295-301. PMID:15301527 doi:10.1021/bi0490439

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