2rfx

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{{Seed}}
 
[[Image:2rfx.png|left|200px]]
[[Image:2rfx.png|left|200px]]
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{{STRUCTURE_2rfx| PDB=2rfx | SCENE= }}
{{STRUCTURE_2rfx| PDB=2rfx | SCENE= }}
===Crystal Structure of HLA-B*5701, presenting the self peptide, LSSPVTKSF===
===Crystal Structure of HLA-B*5701, presenting the self peptide, LSSPVTKSF===
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{{ABSTRACT_PUBMED_18549801}}
{{ABSTRACT_PUBMED_18549801}}
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==Disease==
 
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Known disease associated with this structure: Abacavir hypersensitivity, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=142830 142830]], Spondyloarthropathy, susceptibility to, 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=142830 142830]], Stevens-Johnson syndrome, carbamazepine-induced, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=142830 142830]], Hypoproteinemia, hypercatabolic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=109700 109700]]
 
==About this Structure==
==About this Structure==
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2RFX is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFX OCA].
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[[2rfx]] is a 3 chain structure of [[Beta-2 microglobulin]] and [[Major histocompatibility complex]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFX OCA].
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==See Also==
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*[[Beta-2 microglobulin|Beta-2 microglobulin]]
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*[[Major histocompatibility complex|Major histocompatibility complex]]
==Reference==
==Reference==
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<ref group="xtra">PMID:18549801</ref><references group="xtra"/>
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<ref group="xtra">PMID:018549801</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Archbold, J K.]]
[[Category: Archbold, J K.]]
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[[Category: Membrane]]
[[Category: Membrane]]
[[Category: Mhc i]]
[[Category: Mhc i]]
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[[Category: Polymorphism]]
 
[[Category: Pyrrolidone carboxylic acid]]
[[Category: Pyrrolidone carboxylic acid]]
[[Category: Secreted]]
[[Category: Secreted]]
[[Category: Transmembrane]]
[[Category: Transmembrane]]
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[[Category: Ubl conjugation]]
 
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 10:17:48 2009''
 

Revision as of 09:42, 25 July 2012

Template:STRUCTURE 2rfx

Contents

Crystal Structure of HLA-B*5701, presenting the self peptide, LSSPVTKSF

Template:ABSTRACT PUBMED 18549801

About this Structure

2rfx is a 3 chain structure of Beta-2 microglobulin and Major histocompatibility complex with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Chessman D, Kostenko L, Lethborg T, Purcell AW, Williamson NA, Chen Z, Kjer-Nielsen L, Mifsud NA, Tait BD, Holdsworth R, Almeida CA, Nolan D, Macdonald WA, Archbold JK, Kellerher AD, Marriott D, Mallal S, Bharadwaj M, Rossjohn J, McCluskey J. Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity. Immunity. 2008 Jun;28(6):822-32. PMID:18549801 doi:10.1016/j.immuni.2008.04.020

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